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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKB
All Species:
23.94
Human Site:
T171
Identified Species:
40.51
UniProt:
Q96GD4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GD4
NP_004208.2
344
39280
T171
K
E
L
Q
K
S
C
T
F
D
E
Q
R
T
A
Chimpanzee
Pan troglodytes
XP_511856
395
44529
T222
K
E
L
Q
K
S
R
T
F
D
E
Q
R
T
A
Rhesus Macaque
Macaca mulatta
XP_001118154
562
62706
T389
K
E
L
Q
K
S
R
T
F
D
E
Q
R
T
A
Dog
Lupus familis
XP_849906
346
39574
T171
K
E
L
Q
K
S
H
T
F
D
E
Q
R
T
A
Cat
Felis silvestris
Mouse
Mus musculus
O70126
345
39306
T176
K
E
L
Q
K
S
R
T
F
D
E
Q
R
T
A
Rat
Rattus norvegicus
O55099
343
39216
T174
K
E
L
Q
K
S
G
T
F
D
E
Q
R
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
H153
C
H
S
K
K
V
I
H
R
D
I
K
P
E
N
Chicken
Gallus gallus
XP_425725
409
46456
K241
K
E
L
Q
K
L
T
K
F
D
E
Q
R
T
A
Frog
Xenopus laevis
Q6DE08
361
41717
R187
K
E
L
Q
K
H
G
R
F
D
E
Q
R
S
A
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
T155
F
D
D
Q
R
T
A
T
Y
M
E
E
V
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
K157
F
D
E
P
R
S
A
K
Y
T
Y
Q
V
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
L159
R
D
I
K
P
E
N
L
L
I
G
S
Q
G
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M077
294
33954
H149
L
I
Y
C
H
G
K
H
V
I
H
R
D
I
K
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
P198
K
L
L
R
L
H
G
P
F
N
D
I
L
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
60.3
91.3
N.A.
84.9
84.5
N.A.
61.9
56.9
67.5
66.5
N.A.
44.4
N.A.
53.4
N.A.
Protein Similarity:
100
86.3
60.6
95
N.A.
91.5
90.4
N.A.
72
66.5
78.6
76.1
N.A.
62.5
N.A.
65.1
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
80
73.3
20
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
26.6
80
80
60
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.9
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68
59.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
0
0
0
0
15
58
% A
% Cys:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
8
0
0
0
0
0
0
65
8
0
8
0
8
% D
% Glu:
0
58
8
0
0
8
0
0
0
0
65
8
0
8
8
% E
% Phe:
15
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
22
0
0
0
8
0
0
8
0
% G
% His:
0
8
0
0
8
15
8
15
0
0
8
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
8
0
0
15
8
8
0
8
0
% I
% Lys:
65
0
0
15
65
0
8
15
0
0
0
8
0
0
8
% K
% Leu:
8
8
65
0
8
8
0
8
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
15
% N
% Pro:
0
0
0
8
8
0
0
8
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
65
0
0
0
0
0
0
0
65
8
0
0
% Q
% Arg:
8
0
0
8
15
0
22
8
8
0
0
8
58
0
0
% R
% Ser:
0
0
8
0
0
50
0
0
0
0
0
8
0
15
8
% S
% Thr:
0
0
0
0
0
8
8
50
0
8
0
0
0
50
0
% T
% Val:
0
0
0
0
0
8
0
0
8
0
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
15
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _